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KMID : 0545119970070040267
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Journal of Microbiology and Biotechnology
1997 Volume.7 No. 4 p.267 ~ p.271
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Contraction Behavior of Collagen Gel and Fibroblats Activity in Dermal Equivalent Model
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Yang, Eun Kyung
Lee, Doo Hoon/Park, Sue Nie/Choe, Tae Boo/Park, Jung Keug
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Abstract
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Pseudomonas sp. S-47 degraded 4-chlorobenzoate (4CBA) to 4-chlorocatechol (4CC) that was subsequently ringcleaved to form 5-chloro-2-hydroxymuconic semialdehyde. These intermediate compounds were identified by GC-mass spectrometry and UV-visible spectrophotometry. 5-chloro-2-hydroxymuconic acid converted from 5-chloro-2-hydroxymuconic semialdehyde (5C-2HMS) was dechlorinated to produce 2-hydroxypenta-2,4-dienoic acid (2HP-2,4DA) by the strain. These results indicate that Pseudomonas sp. S-47 degrades 4CBA to 2HP-2,4DA via a novel pathway including the meta-cleavage of 4CC and dechlorination of 5C-2HMS.
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